Immunohistochemical localization of S-100 protein in normal human brain and brain tumors
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چکیده
منابع مشابه
Distribution of immunoreactive S-100 protein in pediatric brain tumors.
The distribution of S-100 proteins was examined in 98 pediatric brain neoplasms with rabbit antiserum to S-100 protein, utilizing the peroxidase-antiperoxidase (PAP) immunohistochemical technique. Positive cytoplasmic immunoreactivity was present in 22 of 24 astrocytomas, both oligodendrogliomas, eight of 13 ependymomas, all 11 choroid plexus tumors, all nine schwannomas, two of six meningiomas...
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BACKGROUND Pituitary tumor-transforming gene (PTTG1) has been implicated in several oncogenic processes. The aim of this study was to determine PTTG expression in brain tumors. MATERIALS AND METHODS We investigated 88 benign and malignant brain tumors. PTTG immunoexpression was evaluated using a scale of 0 to 3. PTTG immunoexpression was nuclear and cytoplasmic in most tumors, except for medu...
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This study is one of the few to characterize immunohistochemically the distribution and localization of Receptor-Associated Protein (RAP) in human autopsy brain. The results show prominent cortical neuronal localization. RAP is clearly identified in large neuronal dendritic/axonal processes. RAP is expressed in both large pyramidal and smaller interneurons. Occasional, much less frequent RAP is...
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The respiratory rates of normal and neoplastic cerebral tissues, and the effect of various anticancer drugs upon them, were measured according to the standard in vitro Warburg technic. The temporal and parietal lobes of normal brain had higher respiratory rates than did the occipital and frontal lobes, and gray matter had a much higher respiratory rate than white matter. Primary and metastatic ...
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The localization of radioantibodies in such normal tissues as liver, kidney, spleen, and adrenal is readily recognized and easily assayed (1). The uptake is relatively rapid and uniform and, when measured in saline-perfused tissues, is usually much higher than the residual back ground localization of labeled normal plasma proteins. In various tumor systems, however, antibody localization has be...
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ژورنال
عنوان ژورنال: Okayama Igakkai Zasshi (Journal of Okayama Medical Association)
سال: 1984
ISSN: 0030-1558,1882-4528
DOI: 10.4044/joma1947.96.1-2_197